The clinical perspective

Why pinpoint localization?

Population-wide screening programs for breast cancer have led to a sharp increase in the detection rate of small and non-palpable breast tumors. As a consequence, surgeons are faced with increasingly challenging procedures as they must locate and operate on these demanding tumors. Surgical localization techniques are indispensable in guiding the surgeon to the right location during breast cancer surgery.

The gold standard is on its last legs

Wire-guided localization has been the gold standard for these procedures ever since its introduction in the 1970s [1]. However, the use of wires is not ideal.
Clinics need to carefully plan their radiology and surgery schedules to prevent delays; surgeons do not have freedom of approach, as the wire entry site may be different from the ideal skin incision location and the wire placement procedure leads to additional pain and stress on an already stressful surgery day for patients.

[1] H. A. Frank, F. M. Hall, and M. L. Steer, “Preoperative Localization of Nonpalpable Breast Lesions Demonstrated by Mammography,” N. Engl. J. Med., vol. 295, no. 5, pp. 259–260, Jul. 1976.

Surgeons demand change

Now, more than 40 years after the introduction of wire-guided localization, it’s time for a change. In recent years, new devices have been developed that overcome many of the disadvantages of wires. Of these, radioactive seed localization is the most prominent newcomer. However, the use of tiny radioactive sources and its strict chain of custody requirements introduce radiation safety concerns, resulting in limited adoption.

Improving care while saving money

At Sirius, we are committed to keeping the healthcare system in balance. We want to deliver on our key promise: when switching from wires to Sirius Pintuition, your costs when measured across the surgical patient care pathway should not increase.

Sharek et al. found that transitioning from wires to radioactive seeds led to a productivity increase of 34% and a decrease in average wait time of 45%. [2]


[2] D. Sharek, et al, “Radioactive seed localization versus wire localization for lumpectomies: A comparison of outcomes,” Am. J. Roentgenol., vol. 204, no. 4, pp. 872–877, 2015.

Read more

Lindenberg et al. concluded that magnetic seed localization could be a cost-efficient localization technique in resecting non-palpable tumors in the Netherlands. [3]

[3] M. Lindenberg, et al., “Early budget impact analysis on magnetic seed localization for non-palpable breast cancer surgery,” PLoS One, vol. 15, no. 5, p. e0232690, May 2020.

Read more

Our promise to the clinic

We strive to be a trusted partner in the clinic and the surgical treatment of cancer patients:

Intuitive and accurate devices that enable surgeons to deliver optimal care

Compelling evidence on performance, outcomes, and health-economics

Affordable solutions that provide value across the patient care pathway

SiriusLink

Sirius Medical recognizes that care pathways are unique for each clinic.
Our SiriusLink program was designed to identify the true time and cost benefit to be gained when switching to Sirius Pintuition, regardless of the type of clinic.
With the data obtained from the SiriusLink program, Sirius wants to help clinics build a business case that is specific for their clinic.

Book an appointment to learn more about SiriusLink