Knowledge

Clinical Insights from Stanford: Using TargetLOC to Navigate with Confidence

Written by Sirius Medical | Apr 15, 2026 9:26:03 AM

Eindhoven, the Netherlands April 13th, 2026

In oncologic surgery, precision means being able to navigate with confidence by not only locating a tumor, but knowing exactly where you are in relation to it throughout the procedure. Surgeons need clarity at the moments that matter most: approaching the target, orienting themselves in tissue, and confirming when they are precisely above the tumor. At Stanford, clinicians are exploring how surgical marker navigation can support this confidence by moving beyond traditional localization approaches. In this article, we share clinical insights from Dr. Jean Bao from Stanford University using TargetLOC™ with the Pintuition® system, and how intuitive feedback can help reduce operation times by 21% compared to other wirefree localization technologies. 

Listen or read to our interview with Dr. Jean Bao from Stanford University and explore how she uses Pintuition® with TargetLOC®  to navigate with confidence - every time.
 
 

 

Question 1: Can you briefly walk us through your study design—time frame, inclusion/exclusion criteria, and how you measured outcomes?

Dr. Jean Bao:
“This was a single‑surgeon, single‑institution, retrospective review of consecutive lumpectomies and excisional biopsies localized with a single marker, either the SAVI SCOUT or the Pintuition seed, between May 2022 and July 2024.

All of these cases were single‑site localizations. Up until June 2023, SAVI SCOUT was the only wireless marker at our institution. Starting August 2023, I’ve been using the Pintuition system exclusively for single‑site localization.

In terms of exclusion criteria, multiple‑localization cases and oncoplastic reconstructive cases were excluded.

We looked at surgical outcomes between the two devices, specifically index retrieval rate, specimen volume, margin rates, and surgery duration.”

 

Question 2: You found a median operative time of 37 minutes with Pintuition versus 50 minutes with SCOUT. What explains this 13‑minute difference?

Dr. Jean Bao:
“The Pintuition cases were shorter than the SAVI SCOUT cases, and that did not come as a surprise to me.

I find the Pintuition system very easy to use. It’s precise, it’s intuitive. I spend less time looking for the marker with Pintuition than with SAVI SCOUT.

I think what contributes to that time difference is the TargetLOC feature that we see with Pintuition when the marker is directly aligned with the probe — that green hashed mark. I think that’s very helpful in telling me exactly where the target is.”  

 

Question 3: What learning curve did your team observe when adopting Pintuition?

Dr. Jean Bao:
“From the surgeon’s perspective, there was minimal learning curve.

To me, I was able to pick it up very, very quickly. It’s just so intuitive to use.

The display is very accurate in terms of the distance between the marker and the probe. There really was no learning curve to speak of for me.”

 

Question 4: How might a 13‑minute shorter operation affect patient experience or OR scheduling at scale?

Dr. Jean Bao:
“The shorter operative time means less anesthesia time for the patient, and potentially being able to do more cases with Pintuition in a day."

 

Question 5: Does fluid or hematoma at the operative site affect device detection?

Dr. Jean Bao:
“The presence of hematoma, or the presence of fluid or bleeding, did not impact detecting the Pintuition seed.

I can say with confidence that we can find the Pintuition seed 100% of the time, regardless of tissue density or the presence of fluid or hematoma.”

 

Question 6: In one sentence, what is the key takeaway of your study, and what should clinicians consider when selecting a wireless localization technology?

Dr. Jean Bao:
“The key takeaway of this study is that the Pintuition system is an excellent localization device.

It works just as well as SAVI SCOUT. If anything, the operative time is shorter, with similar specimen volume and similar margin re‑excision rates.

When selecting a wireless localization device, there are many factors that go into that decision, including cost and contracts. But for me, precision and reliability are very important. I need to be confident that I can always find the marker and get to the target — and the Pintuition system provides that.”   

 

Question 7: What do you see as the future of breast lesion localization and breast surgery more broadly?

Dr. Jean Bao:
“The trend in breast surgery in the recent past has been de‑escalation, and I think we’re continuing down that trend — doing smaller surgeries, fewer surgeries, without compromising oncologic outcomes, while still maximizing cosmetic and functional results.

Because of that, it’s important to be able to precisely localize a lesion, allowing for a smaller excision. And I think the Pintuition system allows for that.”

Beyond confidence in navigation, Stanford’s experience also highlights the broader impact that intuitive surgical marker navigation can have on the operating room. When surgeons can navigate with confidence, without repeated repositioning or uncertainty at the target, procedures can become more efficient and predictable. Shorter, smoother workflows may translate into faster OR turnover, the potential to accommodate more cases per day, and reduced anesthesia time for patients. As healthcare systems continue to focus on efficiency, safety, and value, navigation approaches that support both clinical precision and operational performance are becoming increasingly relevant in modern oncology surgery.

Want to learn more about the Stanford University study? Check out our one-pager!

 Reference: Chinn, J., Earley, M., Dashevsky, B.Z. et al. Comparison of Two Wireless Localization Technologies for Removal of Non-palpable Breast Lesions: SCOUT® Radar Reflector and Pintuition® Magnetic Seed. Ann Surg Oncol 32, 8280–8285 (2025). https://doi.org/10.1245/s10434-025-18354-x